
Management of patient with primary adrenal insufficiency includes both Glucocorticoid and Mineralocorticoid supplementation.

Most common cause is exogenous steroid administration Radiotherapy related hypothalamic/ pituitary suppression Steroid producing tumours certain medication e.g. Less common causes include infiltration like cancer and infections like AIDS, TB etc. And there are two reasons why an individual might lack the ability: Now let’s consider a patient who lacks this ability to do so. It automatically makes as much as the body needs.

Normal adrenal gland responds to serious illness by making up to 10 times more cortisol than it usually makes. It promotes more sodium and water absorption alongside potassium excretion. With regards to concerns of lower levels of adrenal hormones and its impact on patients’ life one must appreciate how important adrenal hormones are in daily life and in critical situations such as medical emergencies.Ĭortisol has several important roles in body including regulating metabolism of fats, proteins and carbohydrates regulations of BP causes a rise in blood sugar levels reduces bone formation reduces inflammation and regulate sleep/awake cycle.Īldosterone maintains BP via Sodium/potassium and water balance.
